Description

2-Chloro-3-Piperazin-1-Yl-Quinoxaline Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic quinoxaline core. This compound is valued for its critical role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel drug candidates, especially within oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of investigational new drugs and specialty APIs.
• Oncology Research: Serves as a core scaffold for developing kinase inhibitors and other targeted cancer therapies.
• CNS Drug Discovery: Used in constructing molecules for potential neurological and psychiatric disorder treatments.
• Chemical Biology & Proteomics: Employed as a molecular probe or tag in studying protein-ligand interactions and enzyme function.
• Agrochemical Research: Investigated as a starting material for novel fungicides or pesticides due to its bioactive quinoxaline structure.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and novel heterocyclic chemistry.

Basic Information

Product Name	2-Chloro-3-Piperazin-1-Yl-Quinoxaline Hydrochloride
CAS No.	55686-36-7
Molecular Formula	C₁₃H₁₅Cl₂N₅
Molecular Weight	312.20 g/mol
Synonyms	2-Chloro-3-(piperazin-1-yl)quinoxaline hydrochloride; 2-Chloro-3-piperazinylquinoxaline HCl; Quinoxaline, 2-chloro-3-(1-piperazinyl)-, hydrochloride; 3-Piperazinyl-2-chloroquinoxaline hydrochloride; 2-Chloro-3-(1-piperazinyl)quinoxaline monohydrochloride; 55686-36-7; 2-Cl-3-Piperazinylquinoxaline HCl
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Piperazin-1-Yl-Quinoxaline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment and allowed to reach ambient temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.