Description

Potassium 3-Methylbutan-2-Olate is a specialized organopotassium compound, also known as potassium pinacolone enolate. This chemical serves as a powerful, non-nucleophilic base and a versatile enolate anion synthon in advanced organic synthesis. It is critical for researchers and process chemists in the pharmaceutical and fine chemical industries who require precise control over deprotonation and carbon-carbon bond formation reactions. Its utility is particularly noted in the synthesis of complex molecules where regioselectivity and mild reaction conditions are paramount.

Application

• As a strong, non-nucleophilic base for the deprotonation of sensitive carbonyl compounds and weak carbon acids.
• Key intermediate in aldol condensation reactions for the construction of complex organic frameworks.
• Employed in the synthesis of pharmaceutical intermediates, particularly for active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Used in fine chemical and agrochemical research for creating novel compounds.
• Acts as a precursor for generating other enolate species under controlled conditions.
• Utilized in academic and industrial R&D for methodological development in synthetic organic chemistry.

Basic Information

Product Name	Potassium 3-Methylbutan-2-Olate
CAS No.	55553-86-1
Molecular Formula	C5H9KO
Molecular Weight	124.22 g/mol
Synonyms	Potassium 3-methylbutan-2-olate; Potassium pinacolone enolate; 3-Methyl-2-butanone, potassium enolate; Potassium 3,3-dimethyl-2-oxobutanolate; Potassium tert-butyl ketone enolate; Pinacolone potassium enolate; 2-Butanone, 3-methyl-, potassium enolato derivative
EINECS	Contact for details

Quality Control

Our Potassium 3-Methylbutan-2-Olate is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity. Production adheres to cGMP principles where applicable, and the material is characterized by modern analytical techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and light-sensitive nature, this material must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from moisture, strong acids, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 95.0%
Potassium Content	30.0 - 32.0 %
Solubility (Test)	Soluble in THF, DMSO; reacts with water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.