Description

Monopotassium Phenylamide is a reactive organometallic reagent used as a potent base and nucleophile in advanced synthetic chemistry. Its value lies in enabling critical deprotonation and substitution reactions that are challenging with conventional bases. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries developing active ingredients and complex organic molecules.

Application

• As a strong, non-nucleophilic base for the generation of sensitive carbanions and enolates in pharmaceutical intermediate synthesis.
• Key reagent in metal-halogen exchange reactions for the preparation of functionalized aryl and heteroaryl building blocks.
• Used in the synthesis of liquid crystal materials and other advanced organic electronic compounds.
• Employed in polymerization initiator systems and catalyst preparation for specialty polymers.
• Facilitates directed ortho-metalation (DoM) strategies to achieve regioselective functionalization of aromatic rings.
• Precursor for the synthesis of other potassium organometallic reagents used in cross-coupling reactions.

Basic Information

Product Name	Monopotassium Phenylamide
CAS No.	19642-99-0
Molecular Formula	C6H6KN
Molecular Weight	131.22 g/mol
Synonyms	Potassium Anilide; Potassium Phenylamide; Benzenamine, Potassium Salt; Phenylpotassium Amide; Aniline, Potassium Derivative; KPhenylNH2; Potassium Aniline
EINECS	Contact for details

Quality Control

Our Monopotassium Phenylamide is manufactured under controlled conditions to ensure high reactivity and consistency. Each batch undergoes rigorous analytical testing, including assay and impurity profiling, to meet the stringent requirements of process chemistry and research applications. A Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area, away from heat and moisture sources. Due to its hygroscopic and easily oxidized nature, the container must be kept sealed under positive pressure of inert gas when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Off-white to beige powder or lumps
Identification (IR)	Conforms
Assay (Titration)	≥ 95.0%
Potassium Content	28.0 - 30.5 %
Solubility (Test in THF)	Complete, clear solution
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.