Description

8-Methoxy-4-(Trimethylsiloxy)-2-Quinolinecarboxylic Acid Trimethylsilyl Ester is a sophisticated, silyl-protected quinoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its primary value lies in enabling complex molecular transformations, particularly in the synthesis of pharmacologically active compounds, by offering reactive sites protected from unwanted side reactions. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable building blocks for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel quinoline-based drug candidates, including potential antimicrobials, anticancer agents, and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides that leverage the quinoline scaffold for enhanced activity.
• Organic Synthesis Reagent: Serves as a protected precursor in multi-step synthetic routes, facilitating reactions at other sites on the quinoline core.
• Material Science Research: Employed in the development of organic electronic materials, ligands for catalysts, and fluorescent dyes due to its modifiable structure.
• Academic & Industrial R&D: A valuable tool for method development and exploring new chemical spaces in heterocyclic chemistry within university and corporate laboratories.

Basic Information

Product Name	8-Methoxy-4-(Trimethylsiloxy)-2-Quinolinecarboxylic Acid Trimethylsilyl Ester
CAS No.	55517-50-5
Molecular Formula	C17H25NO4Si2
Molecular Weight	363.56 g/mol
Synonyms	2-Quinolinecarboxylic acid, 8-methoxy-4-(trimethylsiloxy)-, trimethylsilyl ester; Trimethylsilyl 8-methoxy-4-(trimethylsiloxy)quinoline-2-carboxylate; 8-Methoxy-4-(trimethylsilyloxy)quinoline-2-carboxylic acid trimethylsilyl ester; 4-(Trimethylsiloxy)-8-methoxy-2-quinolinecarboxylic acid trimethylsilyl ester; TMS ester of 8-methoxy-4-(trimethylsiloxy)quinoline-2-carboxylic acid; CAS 55517-50-5
EINECS	Contact for details

Quality Control

Our production of 8-Methoxy-4-(Trimethylsiloxy)-2-Quinolinecarboxylic Acid Trimethylsilyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All materials are characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.