Description

4-Chloro-7-Methoxy-6-Nitroquinazoline is a high-purity, synthetically valuable quinazoline derivative. This compound serves as a critical pharmaceutical intermediate and building block in advanced organic synthesis, particularly for the development of targeted therapeutic agents. It is essential for research and manufacturing in the pharmaceutical, agrochemical, and fine chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of tyrosine kinase inhibitors (TKIs) and other small-molecule drug candidates targeting various cancers and proliferative diseases.
• Agrochemical Research: Used in the development of novel herbicides and fungicides, leveraging its heterocyclic core for biological activity.
• Chemical Synthesis Building Block: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and the construction of complex quinazoline-based libraries.
• Biochemical Research: Acts as a tool compound for studying enzyme inhibition and signal transduction pathways in academic and industrial R&D settings.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals, dyes, and advanced materials requiring specific functionalization.

Basic Information

Product Name	4-Chloro-7-Methoxy-6-Nitroquinazoline
CAS No.	55496-69-0
Molecular Formula	C9H6ClN3O3
Molecular Weight	239.62 g/mol
Synonyms	6-Nitro-7-methoxy-4-chloroquinazoline; 4-Chloro-6-nitro-7-methoxyquinazoline; 7-Methoxy-4-chloro-6-nitroquinazoline; Quinazoline, 4-chloro-7-methoxy-6-nitro-; 4-Chloro-7-methoxy-6-nitro-quinazoline; 55496-69-0 (CAS); 4-Chloro-6-nitro-7-methoxy-quinazoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-7-Methoxy-6-Nitroquinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.