Description

Z-Dl-Phe(4-Cl)-Oh CAS NO 55478-54-1 is a synthetic, non-natural amino acid derivative featuring a racemic (DL) configuration and a para-chloro substitution on the phenylalanine aromatic ring. This specific structural modification makes it a valuable chiral building block and intermediate in advanced organic synthesis. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors. The compound's defined stereochemistry and halogenated side chain are critical for developing novel bioactive molecules and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for protease inhibitors and other targeted therapies.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate a chlorinated phenylalanine residue, altering the peptide's hydrophobicity, receptor binding, and metabolic stability.
• Agrochemical Research: Acts as a precursor in the synthesis of novel herbicides, fungicides, and plant growth regulators that require halogenated aromatic motifs.
• Chemical Biology & Proteomics: Employed as a molecular probe or a building block for activity-based protein profiling (ABPP) and the study of enzyme mechanisms.
• Material Science: Potential monomer for creating specialized polymers with unique optical or electronic properties derived from the chlorophenyl group.
• Academic & Contract Research: Essential reagent for university laboratories and CROs (Contract Research Organizations) conducting methodological studies in asymmetric synthesis and medicinal chemistry.

Basic Information

Product Name	Z-Dl-Phe(4-Cl)-Oh
CAS No.	55478-54-1
Molecular Formula	C17H16ClNO4
Molecular Weight	333.77 g/mol
Synonyms	N-Carbobenzoxy-DL-4-chlorophenylalanine; Z-DL-4-Chlorophenylalanine; Cbz-DL-Phe(4-Cl)-OH; N-(Benzyloxycarbonyl)-DL-4-chlorophenylalanine; DL-4-Chloro-N-carbobenzoxyphenylalanine; (RS)-2-(((Benzyloxy)carbonyl)amino)-3-(4-chlorophenyl)propanoic acid; Z-DL-4-Cl-Phe-OH; N-CBZ-DL-4-chlorophenylalanine
EINECS	Contact for details

Quality Control

Our Z-Dl-Phe(4-Cl)-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	DL-mixture (approx. 50:50)
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.