Description

4-Nitrophenylb-D-Thiomannopyranoside is a specialized synthetic glycoside derivative, serving as a critical chromogenic substrate for enzymatic assays. Its core value lies in enabling precise, colorimetric detection and quantification of specific glycosidase enzyme activity. This compound is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and diagnostic kit manufacturing sectors who require reliable, high-purity biochemical reagents.

Application

• Enzymatic Substrate for Glycosidases: Primary use as a chromogenic substrate for the detection and kinetic study of α-mannosidase and related enzymes.
• Biochemical Research & Assay Development: A key reagent in developing high-throughput screening (HTS) assays for enzyme inhibition studies and drug discovery.
• Diagnostic Kit Manufacturing: Incorporated into clinical diagnostic kits for the detection of specific enzyme deficiencies or biomarkers.
• Quality Control in Biopharma: Used to monitor and validate the activity of enzyme-based therapeutics or processing enzymes in biomanufacturing.
• Microbiology Studies: Employed in research to characterize glycosidase activity in various microorganisms.

Basic Information

Product Name	4-Nitrophenylb-D-Thiomannopyranoside
CAS No.	55385-51-8
Molecular Formula	C12H15NO7S
Molecular Weight	317.32 g/mol
Synonyms	4-Nitrophenyl β-D-thiomannopyranoside; p-Nitrophenyl β-D-thiomannoside; 4-Nitrophenyl 1-thio-β-D-mannopyranoside; PNPTM; β-4-Nitrophenyl thiomannoside; 1-Thio-β-D-mannopyranoside 4-nitrophenyl ester; 4-Nitrophenyl β-D-1-thiomannopyranoside
EINECS	Contact for details

Quality Control

Our 4-Nitrophenylb-D-Thiomannopyranoside is produced under stringent conditions to ensure high purity and batch-to-batch consistency suitable for sensitive biochemical applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic identification (IR, NMR), and specific optical rotation verification. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.