Description

4-Bromobenzamidine Hydrochloride is a high-purity organic building block and a key intermediate in pharmaceutical and agrochemical synthesis. Its value lies in the amidine functional group, which serves as a versatile precursor for constructing heterocyclic compounds and bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and life science industries developing new therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of protease inhibitors, kinase inhibitors, and other small molecule drug candidates.
• Agrochemical Synthesis: Used in the production of novel fungicides, herbicides, and insecticides, leveraging the bromine substituent for further functionalization.
• Chemical Biology & Proteomics Research: Serves as a key reagent in the development of activity-based probes (ABPs) and inhibitors for studying enzyme function.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers and functional materials.
• Organic Synthesis Building Block: Utilized in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the benzamidine moiety into complex molecular architectures.

Basic Information

Product Name	4-Bromobenzamidine Hydrochloride
CAS No.	55368-42-8
Molecular Formula	C7H8BrN2•HCl
Molecular Weight	251.52 g/mol
Synonyms	p-Bromobenzamidine Hydrochloride; 4-Bromobenzenecarboximidamide Hydrochloride; Benzenecarboximidamide, 4-bromo-, hydrochloride (1:1); (4-Bromophenyl)methanimidamide Hydrochloride; 4-Bromo-BzH HCl
EINECS	Contact for details

Quality Control

Our 4-Bromobenzamidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.