Description

Thallous Chloride-201Tl CAS NO 55172-29-7 is a radiochemical compound where the thallium atom is the radioisotope Thallium-201. This product is critical for nuclear medicine and diagnostic imaging applications due to the specific gamma emission properties of Tl-201. It is primarily utilized by radiopharmacies, research institutions, and medical diagnostic facilities for the preparation of radiopharmaceuticals. Strict quality control is essential to ensure its efficacy and safety in clinical settings.

Application

• Myocardial Perfusion Imaging (MPI): As the active pharmaceutical ingredient (API) in Thallium-201 Chloride injection, used in single-photon emission computed tomography (SPECT) to assess blood flow to the heart muscle.
• Radiopharmaceutical Synthesis: Serves as a radioactive precursor or starting material for the synthesis of more complex diagnostic agents in radiopharmacies.
• Oncology and Tumor Imaging: Used in the detection and localization of certain types of tumors, leveraging its uptake mechanisms in viable tissue.
• Nuclear Medicine Research: Employed in preclinical and clinical research to study pharmacokinetics, biodistribution, and the development of new diagnostic protocols.
• Calibration Source: Can be used as a calibration standard for gamma cameras and other radiation detection equipment in medical and laboratory settings.

Basic Information

Product Name	Thallous Chloride-201Tl
CAS No.	55172-29-7
Molecular Formula	¹⁰¹TlCl
Molecular Weight	~239.82 g/mol (for ¹⁰¹TlCl)
Synonyms	Thallium-201 Chloride; Thallium (¹⁰¹Tl) Chloride; Thallous Chloride Tl 201; Thallium Chloride (¹⁰¹Tl); Tl-201 Chloride; Radio-Thallium Chloride; Thallium Monochloride-201; [¹⁰¹Tl]Thallium Chloride
EINECS	Contact for details

Quality Control

Every batch of Thallous Chloride-201Tl is manufactured and tested under strict cGMP conditions for radiopharmaceuticals. Quality assurance includes rigorous testing for radiochemical purity, radionuclidic purity, specific activity, pH, sterility, and apyrogenicity to meet or exceed pharmacopoeial standards (e.g., USP, Ph. Eur.). A comprehensive Certificate of Analysis (CoA) detailing all release specifications is provided with each shipment.

Storage

Preserve in the original, tightly closed, shielded container as supplied. Store in a designated, secure radiation area at controlled room temperature (15-25°C). This material is strictly light-sensitive and must be protected from all light exposure. Adhere to all local, national, and international regulations for the storage and handling of radioactive materials.

Specification

Item	Specification
Appearance	Clear, colorless solution
Identification (Gamma Spectroscopy)	Complies (Principal photon peaks for ¹⁰¹Tl)
Radionuclidic Purity	≥ 99.0% ¹⁰¹Tl at calibration time
Radiochemical Purity (HPLC/TLC)	≥ 95.0% as Thallous Chloride
pH	4.5 - 7.5
Specific Activity	As stated on CoA at calibration date/time
Sterility Test	Sterile
Bacterial Endotoxins (LAL)	< 175 EU/Vial

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.