Description

Trimethyl 2-Phosphonoacrylate is a high-purity organophosphorus compound, specifically the trimethyl ester of 2-phosphonoacrylic acid. This versatile chemical intermediate is valued for its unique reactivity, serving as a key building block in the synthesis of complex molecules. It is essential for research and production in the pharmaceutical, agrochemical, and specialty polymer industries, where it enables the introduction of functional phosphonate groups.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those with bone-targeting or antiviral properties.
• Agrochemical Synthesis: Used in the production of advanced herbicides, plant growth regulators, and other crop protection agents that incorporate phosphonate functionality.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized phosphonate-based ligands used in metal catalysis and coordination chemistry.
• Material Science & Polymer Chemistry: Employed in the synthesis of functional monomers for flame-retardant polymers, adhesives, and coatings with enhanced properties.
• Chemical Research & Development: A valuable reagent for organic synthesis, particularly in Horner-Wadsworth-Emmons (HWE) olefination reactions to form α,β-unsaturated esters.
• Surface Modification Agents: Used to create self-assembled monolayers or to functionalize surfaces with reactive phosphonate groups for biomedical or industrial applications.

Basic Information

Product Name	Trimethyl 2-Phosphonoacrylate
CAS No.	55168-74-6
Molecular Formula	C6H11O5P
Molecular Weight	194.12 g/mol
Synonyms	Trimethyl (2-Phosphonoacrylate); Trimethyl Phosphonoacrylate; 2-(Dimethoxyphosphoryl)acrylic Acid Methyl Ester; Acrylic acid, 2-phosphono-, trimethyl ester; (Methoxycarbonylmethylidene)dimethylphosphonate; Trimethyl 2-(Dimethoxyphosphoryl)acrylate; Phosphonoacrylic Acid Trimethyl Ester
EINECS	Contact for details

Quality Control

Our Trimethyl 2-Phosphonoacrylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Gravity (20°C)	1.20 - 1.30

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.