Description

7-Chloro-2-Fluoro-10-Methoxy-10H-Phenothiaphosphine 10-Oxide is a high-purity, functionalized phenothiaphosphine derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique heterocyclic structure, featuring chlorine, fluorine, and methoxy substituents, makes it a valuable building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), specialty agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Ligand Synthesis: Used for the preparation of specialized phosphine-based ligands for catalysis, enabling more efficient and selective transition metal-catalyzed cross-coupling reactions.
• Agrochemical Research: Serves as a sophisticated intermediate in the development of next-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Employed in the research and development of organic electronic materials, such as components for OLEDs (Organic Light-Emitting Diodes) or charge-transport materials.
• Chemical Biology Probes: Useful for synthesizing molecular probes to study biological processes and enzyme mechanisms due to its modifiable phosphine oxide core.

Basic Information

Product Name	7-Chloro-2-Fluoro-10-Methoxy-10H-Phenothiaphosphine 10-Oxide
CAS No.	55125-05-8
Molecular Formula	C₁₃H₉ClFNOPS
Molecular Weight	313.70 g/mol
Synonyms	7-Chloro-2-fluoro-10-methoxy-10H-phenothiaphosphinine 10-oxide; 10H-Phenothiaphosphinine 10-oxide, 7-chloro-2-fluoro-10-methoxy-; 7-Chloro-2-fluoro-10-methoxyphenothiaphosphinine 10-oxide; Phenothiaphosphine oxide, 7-chloro-2-fluoro-10-methoxy-; 55125-05-8; CAS 55125-05-8
EINECS	Contact for details

Quality Control

Our 7-Chloro-2-Fluoro-10-Methoxy-10H-Phenothiaphosphine 10-Oxide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged manipulations to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.