Description

2-Bromo-2-Methylpropanoyl Cyanide is a versatile and highly reactive organic building block, primarily valued for its role as a key intermediate in advanced chemical synthesis. Its unique structure, featuring both a bromine leaving group and a nitrile functionality, makes it an essential reagent for constructing complex molecular frameworks. This compound is particularly critical for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to introduce functional groups and create novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring branched-chain or cyano-substituted structures.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its reactivity to form potent bioactive compounds.
• Polymer Chemistry: Serves as a functional monomer or initiator in the production of specialty polymers with tailored properties such as thermal stability or specific reactivity.
• Organic Synthesis Reagent: Employed in various name reactions and coupling chemistries to introduce the 2-bromo-2-methylpropanoyl moiety into target molecules.
• Material Science Research: Acts as a building block for creating novel organic materials, including liquid crystals and advanced coatings.
• Chemical Research & Development: A valuable tool for medicinal chemistry and process chemistry in developing new synthetic routes and exploring structure-activity relationships.

Basic Information

Product Name	2-Bromo-2-Methylpropanoyl Cyanide
CAS No.	55106-47-3
Molecular Formula	C5H6BrNO
Molecular Weight	176.01 g/mol
Synonyms	2-Bromo-2-methylpropionyl cyanide; α-Bromoisobutyryl cyanide; 2-Bromo-2-methylpropanenitrile, 1-oxo-; Bromoisobutyronitrile, 1-oxo-; 2-Bromo-2-methylpropionitrile, 1-oxo-; 2-Bromoisobutyryl cyanide; (Bromomethyl)propanedinitrile, 2-methyl-; Isobutyryl cyanide, α-bromo-
EINECS	Contact for details

Quality Control

Our 2-Bromo-2-Methylpropanoyl Cyanide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, GC, and NMR, to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.