Description

(2S)-1,2,3,4-Tetrahydro-1-Hydroxy-4-Oxo-2-Quinolinecarboxylic Acid is a high-purity chiral intermediate with significant synthetic utility. This compound matters for its role as a key building block in the synthesis of complex pharmaceutical molecules, particularly those targeting neurological and cardiovascular pathways. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Organic Synthesis Building Block: Used in asymmetric synthesis and medicinal chemistry for constructing complex quinoline-based heterocycles.
• Research & Development (R&D): Serves as a standard or starting material in academic and industrial laboratories for method development and biological activity studies.
• Fine Chemical Production: Employed in the multi-step synthesis of advanced, high-value specialty chemicals.
• Process Chemistry: Used in route scouting and scale-up activities for new pharmaceutical processes under Good Manufacturing Practice (GMP) guidelines.

Basic Information

Product Name	(2S)-1,2,3,4-Tetrahydro-1-Hydroxy-4-Oxo-2-Quinolinecarboxylic Acid
CAS No.	55030-24-5
Molecular Formula	C10H9NO4
Molecular Weight	207.18 g/mol
Synonyms	(2S)-1,2,3,4-Tetrahydro-1-hydroxy-4-oxoquinoline-2-carboxylic acid; (S)-1-Hydroxy-4-oxo-1,2,3,4-tetrahydroquinoline-2-carboxylic Acid; L-1-Hydroxy-4-oxo-1,2,3,4-tetrahydroquinoline-2-carboxylic Acid; (S)-1,2,3,4-Tetrahydro-1-hydroxy-4-oxo-2-quinolinecarboxylic acid; 1-Hydroxy-4-oxo-1,2,3,4-tetrahydroquinoline-2(S)-carboxylic Acid; Quinoline-2-carboxylic acid derivative; Chiral quinoline intermediate
EINECS	Contact for details

Quality Control

Our (2S)-1,2,3,4-Tetrahydro-1-Hydroxy-4-Oxo-2-Quinolinecarboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and opened under inert atmosphere when handling is required for sensitive applications.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.