Description

(14β,25R)-3β-Hydroxy-5α-Spirost-8-En-11-One CAS NO 54965-96-7 is a high-purity, steroidal sapogenin derivative characterized by its specific spirostan structure. This compound serves as a critical advanced intermediate in the synthesis of complex steroid-based pharmaceuticals and bioactive molecules. It is primarily required by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel therapeutic agents and conducting structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of steroidal drugs, including potential anti-inflammatory, hormonal, and cardiovascular agents.
• Research & Development: Used in academic and industrial R&D for exploring new bioactive compounds and metabolic pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Fine Chemical Synthesis: Intermediate in the multi-step synthesis of complex natural products and specialty chemicals.
• Agrochemical Development: Potential precursor in the research of plant growth regulators or bioactive agrochemicals.
• Biochemical Studies: Tool compound for investigating enzyme interactions and steroidal biosynthesis mechanisms.

Basic Information

Product Name	(14β,25R)-3β-Hydroxy-5α-Spirost-8-En-11-One
CAS No.	54965-96-7
Molecular Formula	C27H40O4
Molecular Weight	428.61 g/mol
Synonyms	11-Ketotigogenin; (25R)-3β-Hydroxy-5α-spirost-8-en-11-one; 5α-Spirost-8-en-11-one, 3β-hydroxy-, (14β,25R)-; Tigogenone; 3β-Hydroxy-5α-spirost-8-en-11-one; 11-Oxotigogenin; Tigogenin-11-one
EINECS	Contact for details

Quality Control

Our (14β,25R)-3β-Hydroxy-5α-Spirost-8-En-11-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance with cGMP and research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.