Description

(25R)-3,3-Dimethoxy-5α-Spirostane is a high-purity, synthetic steroidal sapogenin derivative, serving as a critical advanced intermediate in pharmaceutical synthesis. Its value lies in providing a structurally defined, optically active scaffold for the efficient production of complex steroid-based active pharmaceutical ingredients (APIs). This compound is essential for research institutions and manufacturers in the pharmaceutical and fine chemical industries focused on developing novel therapeutics, including hormone modulators and anti-inflammatory agents.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of steroidal drugs and bioactive molecules.
• Steroid Hormone Research: Used in academic and industrial R&D for studying structure-activity relationships and developing new steroid analogs.
• Process Chemistry: Employed in the development and scale-up of synthetic routes for complex natural products and APIs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(25R)-3,3-Dimethoxy-5α-Spirostane
CAS No.	54965-94-5
Molecular Formula	C₂₉H₄₈O₅
Molecular Weight	476.70 g/mol
Synonyms	3,3-Dimethoxy-5α-spirostan; (25R)-Spirostan-3,3-dimethoxy; 5α-Spirostane-3,3-dimethanol, cyclic acetal; Tigogenin 3,3-dimethyl acetal; (25R)-3,3-Dimethoxyspirostane; 5α,25R-Spirostane-3,3-dimethoxy
EINECS	Contact for details

Quality Control

Our (25R)-3,3-Dimethoxy-5α-Spirostane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates, and specifications can be aligned with customer-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.