Description

(14β,25R)-3β-Hydroxy-5α-Spirostan-15-One CAS NO 54965-91-2 is a high-purity, steroidal sapogenin derivative characterized by its specific hydroxyl and ketone functional groups. This compound serves as a critical advanced intermediate in the synthesis of complex bioactive molecules, offering precise stereochemistry essential for pharmaceutical research and development. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for the production of novel steroid-based therapeutics and reference standards.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel steroid-based drugs and active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new therapeutic agents.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in analytical laboratories.
• Biochemical Research: Utilized as a probe or substrate in enzymatic studies and metabolic pathway investigations related to steroid biochemistry.
• Fine Chemical Synthesis: An intermediate for creating specialized steroidal compounds used in various high-value chemical applications.

Basic Information

Product Name	(14β,25R)-3β-Hydroxy-5α-Spirostan-15-One
CAS No.	54965-91-2
Molecular Formula	C27H42O4
Molecular Weight	430.62 g/mol
Synonyms	15-Oxo-(25R)-5α-spirostan-3β-ol; 3β-Hydroxy-5α-spirostan-15-one; (25R)-5α-Spirostan-3β-ol-15-one; 5α-Spirostan-3β,15-diol-15-one (dehydro derivative); Tigogenone derivative; 15-Ketotigogenin; Steroidal sapogenin ketone; (14β,25R)-3β-Hydroxy-5α-spirostan-15-one
EINECS	Contact for details

Quality Control

Every batch of (14β,25R)-3β-Hydroxy-5α-Spirostan-15-One is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are suitable for research and development applications, with specifications aligning with industry standards for advanced pharmaceutical intermediates. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.