Description

(-)-1-[5-Acetyl-2-Hydroxy-3-(1-Hydroxy-3-Methyl-2-Butenyl)Phenyl]-3-Methyl-1-Butanone CAS NO 54963-61-0 is a high-purity, optically active chemical intermediate characterized by its complex phenolic and ketone structure. This compound is valued for its role as a key chiral building block in sophisticated organic synthesis, particularly where stereochemical control is critical. It is primarily sought by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs) and other advanced materials.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used as a building block in stereoselective reactions to construct molecules with specific three-dimensional configurations.
• Natural Product Synthesis: Serves as a starting material or intermediate in the laboratory synthesis of complex natural products with biological activity.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, including flavors, fragrances, and advanced agrochemicals.
• Biochemical Research: Utilized in research settings to study enzyme interactions, receptor binding, and other stereospecific biological processes.
• Material Science: Potential application in the development of novel chiral polymers or liquid crystals.

Basic Information

Item	Details
Product Name	(-)-1-[5-Acetyl-2-Hydroxy-3-(1-Hydroxy-3-Methyl-2-Butenyl)Phenyl]-3-Methyl-1-Butanone
CAS No.	54963-61-0
Molecular Formula	C20H28O4
Molecular Weight	332.44 g/mol
Synonyms	(-)-Isobavachalcone; (2E)-1-[5-Acetyl-2-hydroxy-3-[(2E)-4-hydroxy-3-methylbut-2-en-1-yl]phenyl]-3-methylbut-1-en-3-one; Isobavachalcone; NSC 365466; Isobavachin; 2',4'-Dihydroxy-4-methoxy-3'-(3-methylbut-2-enyl)chalcone; (E)-Isobavachalcone
EINECS	Contact for details

Quality Control

Our (-)-1-[5-Acetyl-2-Hydroxy-3-(1-Hydroxy-3-Methyl-2-Butenyl)Phenyl]-3-Methyl-1-Butanone is produced under a strict quality management system. Every batch undergoes rigorous analytical testing including HPLC, NMR, and chiral purity analysis to ensure identity, potency, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing purity, chiral excess, and impurity profiles is provided with each shipment to guarantee compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.