Description

1-(2-Bromoethoxy)-4-Iodobenzene is a versatile bifunctional aromatic ether, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both bromoethoxy and iodo substituents on a benzene ring, makes it a valuable precursor for constructing complex molecules through sequential coupling and substitution reactions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing new active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and oncological pathways.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where its halogenated ethoxy side chain enables the introduction of specific bioactive moieties.
• Liquid Crystal & OLED Materials: Serves as a building block for creating mesogenic cores and charge-transport materials in display and lighting technologies.
• Cross-Coupling Reactions: The iodine atom is highly reactive in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira), while the bromoethoxy group allows for further functionalization via nucleophilic substitution.
• Polymer & Dendrimer Chemistry: Acts as a monomer or branching unit for synthesizing specialized polymers, dendrimers, and supramolecular structures with tailored properties.
• Ligand & Catalyst Development: Utilized for constructing complex chelating ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	1-(2-Bromoethoxy)-4-Iodobenzene
CAS No.	54914-17-9
Molecular Formula	C8H8BrIO
Molecular Weight	326.96 g/mol
Synonyms	4-Iodophenyl 2-bromoethyl ether; 2-Bromoethyl 4-iodophenyl ether; 1-Bromo-2-(4-iodophenoxy)ethane; p-Iodophenoxyethyl bromide; 4-(2-Bromoethoxy)iodobenzene; Benzene, 1-(2-bromoethoxy)-4-iodo-; 54914-17-9
EINECS	Contact for details

Quality Control

Our 1-(2-Bromoethoxy)-4-Iodobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting purity, impurity profiles, and physical characteristics. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. The compound is light-sensitive and easily oxidized; therefore, containers should be kept sealed and allowed to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.