Description

3-Mercapto-2-Butanol is a versatile sulfur-containing alcohol with a distinctive thiol functional group. This compound is valued for its role as a key chiral intermediate and building block in the synthesis of complex molecules. It is primarily sought by the pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric synthesis, flavor and fragrance creation, and as a ligand precursor. The product is supplied under high-purity conditions to meet stringent research and manufacturing requirements.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for synthesizing active pharmaceutical ingredients (APIs), particularly in thiol-based drugs.
• Agrochemical Synthesis: Used in the production of pesticides and herbicides where the thiol moiety imparts specific biological activity.
• Flavor & Fragrance Ingredient: Serves as a precursor for sulfur-containing flavor compounds, contributing to meaty, roasted, or savory notes.
• Chemical Research & Development: Employed as a reagent in organic synthesis, especially in Michael addition reactions and nucleophilic substitutions.
• Ligand for Catalysis: Acts as a precursor for chiral ligands used in asymmetric catalysis to produce enantiomerically pure compounds.
• Polymer Modification: Utilized to introduce thiol groups into polymer chains for cross-linking or to alter material properties.

Basic Information

Product Name	3-Mercapto-2-Butanol
CAS No.	54812-86-1
Molecular Formula	C4H10OS
Molecular Weight	106.19 g/mol
Synonyms	2-Butanol, 3-mercapto-; 3-Mercaptobutan-2-ol; (±)-3-Mercapto-2-butanol; 3-Sulfanylbutan-2-ol; DL-3-Mercapto-2-butanol; 3-Hydroxy-2-butanethiol; 2,3-Dihydroxybutyl mercaptan (related); Thiobutylene glycol
EINECS	Contact for details

Quality Control

Our 3-Mercapto-2-Butanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (IR, NMR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C to minimize oxidation and prolong shelf life. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.