Description

5-Chloro-1,2,3,4-Tetrahydro-Quinolin-8-Ol is a versatile heterocyclic organic compound that serves as a key synthetic intermediate in advanced chemical manufacturing. Its unique fused ring structure, featuring both a tetrahydroquinoline core and a phenolic hydroxyl group, makes it a valuable building block for creating complex molecules with specific biological or material properties. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to its tetrahydroquinoline scaffold.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where its chlorinated aromatic system can be leveraged for bioactivity.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a starting material for developing electron-transporting or host materials in OLED devices, benefiting from its rigid, planar structure.
• Ligand for Catalysis: Can be functionalized to create novel ligands for transition metal catalysts used in asymmetric synthesis and cross-coupling reactions.
• Dye and Pigment Intermediate: Serves as a building block for synthesizing specialized dyes and organic pigments, utilizing its aromatic character and substitution sites.
• Academic and Contract Research: Employed in university and CRO laboratories for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Item	Details
Product Name	5-Chloro-1,2,3,4-Tetrahydro-Quinolin-8-Ol
CAS No.	54810-34-3
Molecular Formula	C9H10ClNO
Molecular Weight	183.63 g/mol
Synonyms	8-Hydroxy-5-chloro-1,2,3,4-tetrahydroquinoline; 5-Chloro-8-hydroxy-1,2,3,4-tetrahydroquinoline; 5-Chloro-8-tetrahydroquinolinol; 54810-34-3; 5-Chloro-8-hydroxy-THQ; 5-Cl-8-OH-THQ
EINECS	Contact for details

Quality Control

Our 5-Chloro-1,2,3,4-Tetrahydro-Quinolin-8-Ol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.