Description

6-Chloro-1-Ethyl-4-Hydroxy-3-Nitro-1H-Quinolin-2-One is a specialized quinolinone derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique substitution pattern makes it a valuable building block for the development of novel pharmacologically active compounds and functional materials. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create new molecules with targeted properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways where the quinolinone scaffold is active.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators, leveraging its heterocyclic structure for bioactivity.
• Material Science: Acts as a building block for creating advanced organic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic electronics.
• Chemical Synthesis: Serves as a versatile substrate for further functionalization (e.g., reduction of the nitro group, substitution reactions) to create a diverse library of chemical entities for screening.
• Academic & Industrial R&D: Fundamental reagent for methodological studies in organic synthesis and for exploring new chemical reactions involving nitro- and hydroxy-substituted heterocycles.

Basic Information

Product Name	6-Chloro-1-Ethyl-4-Hydroxy-3-Nitro-1H-Quinolin-2-One
CAS No.	54675-44-4
Molecular Formula	C₁₁H₉ClN₂O₄
Molecular Weight	268.65 g/mol
Synonyms	6-Chloro-1-ethyl-4-hydroxy-3-nitroquinolin-2(1H)-one; 3-Nitro-6-chloro-1-ethyl-4-hydroxy-1H-quinolin-2-one; 1-Ethyl-6-chloro-4-hydroxy-3-nitro-1H-quinolin-2-one; 4-Hydroxy-6-chloro-1-ethyl-3-nitroquinolin-2(1H)-one; Quinolin-2-one, 6-chloro-1-ethyl-4-hydroxy-3-nitro-; 54675-44-4; 6-Chloro-1-ethyl-4-hydroxy-3-nitro-2-quinolone
EINECS	Contact for details

Quality Control

Our 6-Chloro-1-Ethyl-4-Hydroxy-3-Nitro-1H-Quinolin-2-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. We employ advanced analytical techniques to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.