Description

(S)-2-Amino-4-Oxo-4-Phenylbutanoic Acid Hydrochloride is a high-purity chiral amino acid derivative, specifically the hydrochloride salt of the (S)-enantiomer. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, valued for its defined stereochemistry and functional groups. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for protease inhibitors and other enzyme-targeted drugs.
• Peptide Chemistry: Used in the synthesis of non-natural amino acid residues for constructing modified peptides with enhanced stability or biological activity.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to introduce chirality into complex molecular frameworks.
• Biochemical Research: Serves as a standard or reagent in enzymatic studies and metabolic pathway investigations.
• Chemical Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical laboratories.

Basic Information

Product Name	(S)-2-Amino-4-Oxo-4-Phenylbutanoic Acid Hydrochloride
CAS No.	54631-37-7
Molecular Formula	C10H12ClNO3
Molecular Weight	229.66 g/mol
Synonyms	(S)-2-Amino-4-oxo-4-phenylbutanoic acid hydrochloride; (S)-4-Oxo-4-phenyl-2-aminobutanoic acid hydrochloride; (S)-α-Aminosuccinanilic acid hydrochloride; L-2-Amino-4-oxo-4-phenylbutyric acid hydrochloride; (S)-APBA hydrochloride; (2S)-2-Amino-4-oxo-4-phenylbutanoic acid hydrochloride; NSC 334365; (S)-2-Amino-4-phenyl-4-oxobutanoic acid hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-2-Amino-4-Oxo-4-Phenylbutanoic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.