Description

Potassium Tri-sec-Butylborohydride is a highly reactive, sterically hindered borohydride reagent, commonly known as K-Selectride®. This powerful reducing agent is valued for its exceptional selectivity in reducing sterically hindered ketones and its utility in stereoselective synthesis. It is a critical material for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Selective Reduction of Ketones: Primary application for the stereoselective reduction of sterically hindered, cyclic, and bicyclic ketones to produce specific alcohol isomers.
• Pharmaceutical Intermediate Synthesis: Key reagent in the synthesis of complex chiral intermediates for active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Employed in catalytic and stoichiometric processes to establish chiral centers with high enantiomeric excess.
• Fine Chemical Manufacturing: Used in the production of specialty fragrances, flavors, and advanced organic materials.
• Polymer Chemistry: Can act as an initiator or modifying agent in the synthesis of specialized polymers.
• Academic & Industrial R&D: A staple reagent in research laboratories for methodological development and exploratory synthesis.

Basic Information

Product Name	Potassium Tri-sec-Butylborohydride
CAS No.	54575-50-7
Molecular Formula	C12H28BK
Molecular Weight	222.26 g/mol
Synonyms	K-Selectride®; Potassium Tri(sec-butyl)borohydride; Potassium Tri-sec-butylborohydride; Potassium Tris(2-butyl)borohydride; Potassium Tri-secondary-butylborohydride; Borate(1-), tri(2-butyl)hydro-, potassium; Potassium hydrotri(sec-butyl)borate; Potassium tri-s-butylborohydride
EINECS	Contact for details

Quality Control

Our Potassium Tri-sec-Butylborohydride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high reactivity. Typical purity is specified as a 1.0M solution in tetrahydrofuran (THF). Quality is verified through rigorous analytical testing including titration for assay and impurity profiling. A Certificate of Analysis (COA) detailing purity, concentration, and solvent content is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C. This material is highly moisture-sensitive (hygroscopic) and easily oxidized. Keep away from heat, sparks, and open flames. Use only in a well-ventilated fume hood.

Specification

Item	Specification
Appearance	Colorless to slightly yellow solution
Concentration (in THF)	1.0 M
Assay (Titration)	≥ 95.0%
Solvent (THF)	Balance
Water Content (Karl Fischer)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.