Description

trans-4-tert-Butyl-Cyclohexylamine Hydrochloride is a high-purity, stereochemically defined organic salt used as a critical chiral building block and intermediate in advanced chemical synthesis. Its value lies in the rigid, bulky tert-butyl-cyclohexyl backbone, which imparts unique steric and electronic properties to final compounds. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where the specific stereochemistry influences biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands in asymmetric catalysis and organometallic complexes.
• Specialty Polymer Additive: Acts as a monomer or curing agent in high-performance polymers, coatings, and resins to modify thermal and mechanical properties.
• Chemical Research & Development: A valuable reagent for medicinal chemistry, process chemistry, and academic research exploring new synthetic methodologies.
• Fine Chemical Production: Employed in the multi-step synthesis of complex dyes, pigments, and other performance chemicals.

Basic Information

Product Name	trans-4-tert-Butyl-Cyclohexylamine Hydrochloride
CAS No.	54572-02-0
Molecular Formula	C10H22ClN
Molecular Weight	191.74 g/mol
Synonyms	trans-4-(tert-Butyl)cyclohexanamine hydrochloride; (1r,4r)-4-(tert-Butyl)cyclohexanamine hydrochloride; 4-tert-Butylcyclohexylamine hydrochloride (trans); 4-(1,1-Dimethylethyl)cyclohexanamine hydrochloride (trans); trans-4-tert-Butylcyclohexylamine HCl; 4-tert-Butyl-1-aminocyclohexane hydrochloride; 4-(tert-Butyl)cyclohexylamine hydrochloride (trans isomer); Amine 220 hydrochloride
EINECS	Contact for details

Quality Control

Our trans-4-tert-Butyl-Cyclohexylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets stringent specifications for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (trans isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.