Description

2-Deoxyglucose-1-Phosphate is a phosphorylated derivative of 2-deoxyglucose, a key analog used to study glucose metabolism. This compound is a vital biochemical tool for investigating the hexokinase and glucose-6-phosphate dehydrogenase pathways, offering insights into cellular energy regulation. It is essential for researchers and manufacturers in the fields of biochemistry, metabolic research, and pharmaceutical development.

Application

• Biochemical Research: Critical substrate and inhibitor for studying glycolysis, the pentose phosphate pathway, and glucose metabolism in cell cultures and enzymatic assays.
• Pharmaceutical Development: Used in the research and screening of potential therapeutic agents targeting metabolic disorders, such as diabetes and cancer.
• Enzymology Studies: Serves as a specific substrate for enzymes like phosphoglucose isomerase and as an inhibitor for hexokinase, aiding in kinetic and mechanistic studies.
• Diagnostic Reagent Manufacturing: A key component in formulating diagnostic kits and reagents for clinical laboratories to assess metabolic enzyme function.
• Academic & Institutional Research: Fundamental tool in university and institutional labs for teaching and advanced research in biochemistry and molecular biology.
• Metabolic Pathway Analysis: Employed in tracer studies and metabolic flux analysis to map and quantify intracellular metabolic networks.

Basic Information

Product Name	2-Deoxyglucose-1-Phosphate
CAS No.	54482-78-9
Molecular Formula	C6H13O9P
Molecular Weight	260.14 g/mol
Synonyms	2-Deoxy-D-glucose 1-Phosphate; 2-Deoxyglucose-1-P; 2-DG-1-P; 2-Deoxy-D-arabino-hexose 1-phosphate; 1-Phospho-2-deoxy-D-glucose; D-2-Deoxyglucose 1-phosphate; 2-Desoxyglucose-1-phosphate; (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-methyloxolane-3,4-diol 1-dihydrogen phosphate
EINECS	Contact for details

Quality Control

Our 2-Deoxyglucose-1-Phosphate is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR), to ensure it meets high-purity research-grade standards. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive). For long-term storage, keep the container tightly sealed under an inert atmosphere to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.