Description

2-Deoxyglucose-1,6-Bisphosphate is a phosphorylated derivative of 2-deoxyglucose, a well-known glucose analog and metabolic inhibitor. This compound is a critical biochemical tool for studying glycolysis, hexokinase activity, and cellular energy metabolism pathways. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical development, and diagnostic reagent sectors for enzyme assays and metabolic research.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for investigating hexokinase and glucose-6-phosphate isomerase activity within the glycolytic pathway.
• Metabolic Pathway Analysis: Serves as a key tool for probing and modulating cellular glucose metabolism in both in vitro and cell-based assay systems.
• Pharmaceutical Development: Employed in early-stage drug discovery research targeting metabolic disorders, such as cancer, where altered glycolysis is a hallmark.
• Diagnostic Reagent Manufacturing: A potential component in the formulation of specialized diagnostic kits for measuring specific enzyme activities in clinical or research laboratories.
• Enzyme Kinetics: Essential for determining kinetic parameters (Km, Vmax) of glycolytic enzymes to understand regulation and inhibition mechanisms.

Basic Information

Product Name	2-Deoxyglucose-1,6-Bisphosphate
CAS No.	54428-44-3
Molecular Formula	C6H14O12P2
Molecular Weight	340.12 g/mol
Synonyms	2-Deoxy-D-glucose 1,6-bisphosphate; 2-DG-1,6-bisP; 2-Deoxyglucose-1,6-diphosphate; 1,6-Bis-O-phosphono-2-deoxy-D-glucopyranose; 2-Deoxy-D-arabino-hexose 1,6-bis(dihydrogen phosphate); D-2-Deoxyglucose 1,6-bisphosphate
EINECS	Contact for details

Quality Control

Our 2-Deoxyglucose-1,6-Bisphosphate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the container to reach ambient temperature before opening to minimize moisture absorption. For prolonged storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content	≤ 5.0%
Solubility	Soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.