Description

Thiophene-3-Ol, 4-Chloro-2,5-Dihydro-, 1,1-Dioxide is a specialized heterocyclic sulfone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where its unique chlorinated dihydrothiophene dioxide structure enables the construction of complex molecular architectures. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the fine chemical, pharmaceutical, and agrochemical industries.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting new therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, such as herbicides and fungicides, leveraging its reactive chlorinated sulfone moiety.
• Material Science Research: Serves as a monomer or precursor in the development of specialized polymers and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed as a reactive handle or linker in the design of chemical probes and bioconjugation reagents for studying biological systems.
• Catalyst & Ligand Development: Acts as a precursor for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	Thiophene-3-Ol, 4-Chloro-2,5-Dihydro-, 1,1-Dioxide
CAS No.	54391-36-5
Molecular Formula	C4H5ClO3S
Molecular Weight	168.60 g/mol
Synonyms	4-Chloro-2,5-dihydrothiophene-3-ol 1,1-dioxide; 4-Chloro-3-hydroxy-2,5-dihydrothiophene 1,1-dioxide; 3-Hydroxy-4-chloro-2,5-dihydrothiophene 1,1-dioxide; 4-Chloro-3-hydroxy-2,3-dihydrothiophene 1,1-dioxide; 4-Chloro-2,5-dihydro-3-thiophenol S,S-dioxide
EINECS	Contact for details

Quality Control

Our Thiophene-3-Ol, 4-Chloro-2,5-Dihydro-, 1,1-Dioxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. Certificates of Analysis (COA) with full specification data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.