Description

8-Bromo-2-(Methylthio)Pyrazolo[1,5-A][1,3,5]Triazin-4-Ol CAS NO 54346-35-9 is a high-purity, heterocyclic organic compound belonging to the pyrazolotriazine class, serving as a critical advanced pharmaceutical intermediate (API intermediate). Its unique fused-ring structure with bromine and methylthio substituents makes it a valuable versatile building block for medicinal chemistry research and development. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for synthesizing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in oncology and antiviral research.
• Medicinal Chemistry Building Block: Used for structure-activity relationship (SAR) studies and lead optimization due to its reactive bromine and sulfur sites.
• Agrochemical Research: Serves as a scaffold for developing new herbicides, fungicides, or insecticides.
• Chemical Biology Probe Development: Utilized in creating tool compounds for studying biological pathways and target validation.
• Organic Synthesis Research: Employed in academic and industrial labs for developing novel heterocyclic coupling reactions and methodologies.
• Material Science Precursor: Investigated for the synthesis of specialized organic electronic materials or ligands for catalysis.

Basic Information

Item	Details
Product Name	8-Bromo-2-(Methylthio)Pyrazolo[1,5-A][1,3,5]Triazin-4-Ol
CAS No.	54346-35-9
Molecular Formula	C7H5BrN4OS
Molecular Weight	273.11 g/mol
Synonyms	8-Bromo-2-(methylthio)-4H-pyrazolo[1,5-a][1,3,5]triazin-4-one; 8-Bromo-2-methylsulfanyl-4H-pyrazolo[1,5-a][1,3,5]triazin-4-one; 54346-35-9; 8-Bromo-2-(methylthio)pyrazolo[1,5-a][1,3,5]triazin-4-ol; 8-Bromo-2-methylthio-pyrazolo[1,5-a][1,3,5]triazin-4-ol; 8-Bromo-2-(methylmercapto)pyrazolo[1,5-a][1,3,5]triazin-4-ol
EINECS	Contact for details

Quality Control

Our 8-Bromo-2-(Methylthio)Pyrazolo[1,5-A][1,3,5]Triazin-4-Ol is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of research and development applications, and we can support custom synthesis to meet specific project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.