Description

Octahydro-2H-quinolizin-3-ol is a saturated nitrogen-containing heterocyclic alcohol, a versatile building block in advanced organic synthesis. This compound is valued for its rigid, fused bicyclic structure, which serves as a key chiral intermediate in the production of complex pharmaceutical molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for developing active pharmaceutical ingredients (APIs) and other high-value specialty compounds.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of alkaloid-based pharmaceuticals and complex therapeutic agents.
• Asymmetric Synthesis: Used as a scaffold or chiral auxiliary in stereoselective reactions to construct molecules with specific three-dimensional configurations.
• Ligand and Catalyst Development: Serves as a backbone for creating novel ligands and organocatalysts used in homogeneous catalysis.
• Agrochemical Research: Employed in the research and development of new crop protection agents and plant growth regulators.
• Fragrance and Flavor Chemistry: Potential use in synthesizing novel aroma chemicals due to its complex, polycyclic structure.
• Academic and R&D: A valuable compound for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	Octahydro-2H-quinolizin-3-ol
CAS No.	54308-61-1
Molecular Formula	C9H17NO
Molecular Weight	155.24 g/mol
Synonyms	3-Hydroxyoctahydro-2H-quinolizine; 2H-Quinolizin-3-ol, octahydro-; Octahydro-2H-quinolizin-3-ol; 3-Quinolizidinol; (3R)-Octahydro-2H-quinolizin-3-ol (for enantiopure form); (3S)-Octahydro-2H-quinolizin-3-ol (for enantiopure form); Quinolizidin-3-ol
EINECS	Contact for details

Quality Control

Our Octahydro-2H-quinolizin-3-ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and chiral purity verification where applicable, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for enantiopure grades)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.