Description

1,6-Dideoxy-1,1-Bis(Ethylsulfonyl)-L-Mannitol is a specialized chiral building block and synthetic intermediate of significant interest in advanced organic synthesis. Its unique structure, featuring deoxy and ethylsulfonyl groups on a mannitol backbone, makes it a valuable precursor for the development of complex molecules, particularly in pharmaceutical research. This compound is primarily utilized by R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), carbohydrate-based drugs, and sophisticated fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, including antiviral and anticancer compounds.
• Carbohydrate Chemistry Research: Used in the synthesis of modified sugars, nucleosides, and glycomimetics for biological studies and drug discovery.
• Asymmetric Synthesis: Serves as a starting material or auxiliary in stereoselective reactions to construct complex molecular architectures with high enantiomeric purity.
• Fine Chemical Production: Employed in the multi-step synthesis of high-value specialty chemicals for agrochemical and material science applications.
• Academic & Industrial R&D: A valuable tool for investigating new synthetic methodologies and reaction pathways in organic chemistry laboratories.

Basic Information

Product Name	1,6-Dideoxy-1,1-Bis(Ethylsulfonyl)-L-Mannitol
CAS No.	54253-49-5
Molecular Formula	C₁₀H₂₀O₈S₂
Molecular Weight	332.39 g/mol
Synonyms	L-1,6-Dideoxy-1,1-bis(ethylsulfonyl)mannitol; 1,1-Bis(ethylsulfonyl)-1,6-dideoxy-L-mannitol; (2R,3R,4R,5R)-1,6-Dideoxy-1,1-bis(ethylsulfonyl)hexane-2,3,4,5-tetrol; Dideoxybis(ethylsulfonyl)mannitol; L-Mannitol, 1,6-dideoxy-1,1-bis(ethylsulfonyl)-; 54253-49-5; 1,6-Dideoxy-1,1-di(ethylsulfonyl)-L-mannitol
EINECS	Contact for details

Quality Control

Our 1,6-Dideoxy-1,1-Bis(Ethylsulfonyl)-L-Mannitol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.