Description

2-Chloro-N-(1,3-dioxolan-2-ylmethyl)-N-(2,6-dimethylphenyl)acetamide is a specialized acetamide derivative featuring a chloroacetamide core functionalized with a dioxolane-protected aldehyde group and a sterically hindered dimethylphenyl substituent. This unique molecular architecture makes it a valuable chemical intermediate for advanced synthesis, particularly in the development of pharmaceuticals and agrochemicals where precise steric and electronic properties are required. It is primarily sought by R&D chemists and process development teams in the fine chemical, pharmaceutical, and crop protection industries for constructing complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting neurological or metabolic pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its acetamide backbone for bioactivity.
• Chemical Synthesis: Serves as a versatile precursor for introducing the N-(2,6-dimethylphenyl)acetamide moiety into more complex molecular frameworks.
• Material Science: Potential intermediate for synthesizing specialized polymers or ligands for catalytic systems.
• Academic & Industrial R&D: A valuable tool compound for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	2-Chloro-N-(1,3-dioxolan-2-ylmethyl)-N-(2,6-dimethylphenyl)acetamide
CAS No.	54237-74-0
Molecular Formula	C₁₄H₁₈ClNO₃
Molecular Weight	283.75 g/mol
Synonyms	2-Chloro-N-(2,6-dimethylphenyl)-N-[(1,3-dioxolan-2-yl)methyl]acetamide; Acetamide, 2-chloro-N-(1,3-dioxolan-2-ylmethyl)-N-(2,6-dimethylphenyl)-; N-(1,3-Dioxolan-2-ylmethyl)-2-chloro-N-(2,6-dimethylphenyl)acetamide; 2-Chloro-N-(2,6-xylyl)-N-[(1,3-dioxolan-2-yl)methyl]acetamide; Glycine, N-(1,3-dioxolan-2-ylmethyl)-N-(2,6-dimethylphenyl)-, 2-chloro-
EINECS	Contact for details

Quality Control

Our 2-Chloro-N-(1,3-dioxolan-2-ylmethyl)-N-(2,6-dimethylphenyl)acetamide is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical intermediate applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.