Description

7-p-Toluenesulfonylhydrazide Cholesterol 3-Acetate is a specialized cholesterol derivative functionalized with a tosylhydrazide group, serving as a key synthetic intermediate in advanced organic and medicinal chemistry. This compound is valued for its unique reactivity, particularly in the controlled formation of carbon-carbon double bonds via the Shapiro reaction, enabling the synthesis of complex, high-value molecules. It is primarily required by research institutions and pharmaceutical development laboratories for the synthesis of novel steroidal compounds, drug candidates, and other fine chemicals where precise structural modification is critical.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel steroidal drugs and active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial R&D for exploring new synthetic pathways and creating molecular libraries.
• Olefination Reagent: Employed in the Shapiro reaction to generate alkenes from carbonyl compounds under mild conditions.
• Steroid Chemistry: Facilitates specific modifications to the cholesterol backbone for creating analogs with targeted biological activity.
• Fine Chemical Synthesis: Serves as a precursor in the multi-step synthesis of complex organic molecules for various high-tech applications.

Basic Information

Item	Detail
Product Name	7-p-Toluenesulfonylhydrazide Cholesterol 3-Acetate
CAS No.	54201-67-1
Molecular Formula	C36H56N2O4S
Molecular Weight	612.90 g/mol
Synonyms	Cholest-5-en-3β-yl acetate 7-(p-toluenesulfonylhydrazone); 7-Tosylhydrazone of Cholesteryl Acetate; Cholesterol 3-acetate 7-tosylhydrazone; 3β-Acetoxycholest-5-ene 7-tosylhydrazone; (3β)-3-(Acetyloxy)cholest-5-en-7-ylidene]-p-toluenesulfonohydrazide; 7-(p-Toluenesulfonylhydrazono)cholesteryl acetate
EINECS	Contact for details

Quality Control

Our 7-p-Toluenesulfonylhydrazide Cholesterol 3-Acetate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.