Description

3-Benzyloxycyclobutane-1,1-Dicarboxylic Acid Diethyl Ester is a high-purity, specialty organic building block of significant interest in advanced synthetic chemistry. Its unique cyclobutane core functionalized with a benzyloxy group and diester moieties makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for constructing constrained ring systems.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the cyclobutane structure can impart unique biological activity.
• Material Science Research: Acts as a precursor for monomers or ligands in the synthesis of advanced polymers, resins, or metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis, including ring-opening, cross-coupling, and ester transformation reactions.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various technological applications.

Basic Information

Product Name	3-Benzyloxycyclobutane-1,1-Dicarboxylic Acid Diethyl Ester
CAS No.	54166-15-3
Molecular Formula	C₁₇H₂₂O₅
Molecular Weight	306.35 g/mol
Synonyms	Diethyl 3-(benzyloxy)cyclobutane-1,1-dicarboxylate; 1,1-Cyclobutanedicarboxylic acid, 3-(phenylmethoxy)-, diethyl ester; 3-(Benzyloxy)cyclobutane-1,1-dicarboxylic acid diethyl ester; Ethyl 3-benzyloxycyclobutane-1,1-dicarboxylate; Diethyl 3-benzyloxy-1,1-cyclobutanedicarboxylate
EINECS	Contact for details

Quality Control

Our 3-Benzyloxycyclobutane-1,1-Dicarboxylic Acid Diethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (by HPLC), identity (by IR/NMR), and impurity profiles are available for every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.