Description

5-[3-(Trifluoromethyl)Phenyl]-2-Furoic Acid is a high-value fluorinated aromatic building block and intermediate. This compound matters for its unique trifluoromethylphenyl moiety, which imparts desirable properties like metabolic stability and enhanced lipophilicity to target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for anti-inflammatory and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the production of fluorinated liquid crystals for advanced display technologies.
• Organic Electronics: Employed in the synthesis of specialized organic semiconductors and charge-transport materials.
• Chemical Research: A versatile building block for Suzuki-Miyaura and other cross-coupling reactions to create complex biaryl structures.
• Fluorine Chemistry Studies: Used in academic and industrial labs to study the effects of fluorine substitution on molecular properties and reactivity.

Basic Information

Product Name	5-[3-(Trifluoromethyl)Phenyl]-2-Furoic Acid
CAS No.	54022-99-0
Molecular Formula	C12H7F3O3
Molecular Weight	256.18 g/mol
Synonyms	3'-(Trifluoromethyl)[1,1'-biphenyl]-2-carboxylic acid, 5-(3-(Trifluoromethyl)phenyl)furan-2-carboxylic acid, 2-Furoic acid, 5-[3-(trifluoromethyl)phenyl]-, α-(3-Trifluoromethylphenyl)-2-furancarboxylic acid, 5-(m-Trifluoromethylphenyl)-2-furoic acid, 3-Trifluoromethylphenyl-2-furancarboxylic acid, 5-(3-Trifluoromethylphenyl)furan-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-[3-(Trifluoromethyl)Phenyl]-2-Furoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.