Description

8-Amino-1,2,3,4-tetrahydroquinoline is a versatile heterocyclic amine building block of significant importance in advanced organic synthesis. Its fused quinoline-tetrahydroquinoline structure with a primary amino group makes it a critical intermediate for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries, where it serves as a precursor for active pharmaceutical ingredients (APIs), functional dyes, and ligands.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of various pharmacologically active compounds, including central nervous system (CNS) agents and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging its heterocyclic scaffold.
• Organic Ligand Precursor: Serves as a starting material for creating chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of advanced functional dyes and organic pigments.
• Research & Development: A valuable building block in medicinal chemistry and material science research for exploring new chemical entities.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fine chemicals and specialty molecules.

Basic Information

Product Name	8-Amino-1,2,3,4-tetrahydroquinoline
CAS No.	54012-92-9
Molecular Formula	C9H12N2
Molecular Weight	148.21 g/mol
Synonyms	1,2,3,4-Tetrahydro-8-quinolinamine; 8-Aminotetrahydroquinoline; 8-Amino-1,2,3,4-tetrahydroquinoline; 5,6,7,8-Tetrahydro-8-quinolinamine; 8-Amino-5,6,7,8-tetrahydroquinoline; 8-Amino-THQ; 8-ATQ
EINECS	Contact for details

Quality Control

Our 8-Amino-1,2,3,4-tetrahydroquinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.