Description

Tetrahydro-2,5-Dimethyl-2H-Pyranmethanol is a versatile cyclic ether alcohol with a unique structural motif, serving as a valuable intermediate in advanced organic synthesis. Its significance lies in its ability to introduce functionalized tetrahydropyran moieties, which are key structural components in pharmaceuticals, agrochemicals, and fine chemicals. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, flavor & fragrance, and specialty chemical industries seeking to build complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing chiral tetrahydropyran or spirocyclic structures.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where the tetrahydropyran ring enhances biological activity.
• Flavor & Fragrance Ingredient: Serves as a precursor for musk analogs and other complex aroma chemicals, contributing woody, amber, or sweet olfactory notes.
• Ligand & Catalyst Development: Employed in the creation of chiral ligands and organocatalysts for asymmetric synthesis applications.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for specialty polymers, imparting specific solubility or thermal properties.
• Organic Synthesis Reagent: A versatile reagent for constructing oxygen-containing heterocycles and for introducing protected hydroxyl functionality in multi-step syntheses.

Basic Information

Product Name	Tetrahydro-2,5-Dimethyl-2H-Pyranmethanol
CAS No.	54004-46-5
Molecular Formula	C8H16O2
Molecular Weight	144.21 g/mol
Synonyms	2,5-Dimethyltetrahydro-2H-pyran-2-methanol; (Tetrahydro-2,5-dimethyl-2H-pyran-2-yl)methanol; 2-(Hydroxymethyl)-2,5-dimethyltetrahydropyran; 2,5-Dimethyl-2-tetrahydropyranylmethanol; Dihydro-2,5-dimethyl-2H-pyran-2-methanol
EINECS	Contact for details

Quality Control

Our Tetrahydro-2,5-Dimethyl-2H-Pyranmethanol is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting purity, assay, and impurity profiles are available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and heat sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.450 - 1.460
Specific Gravity (20°C)	0.950 - 0.980

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.