Description

4-Hydroxy-7-Trifluoromethoxyquinoline is a high-purity, specialized quinoline derivative of significant interest in advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of novel active ingredients. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors seeking to incorporate its unique trifluoromethoxy-substituted quinoline scaffold.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system and anti-infective applications.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline core.
• Material Science: Serves as a building block for advanced organic electronic materials, including light-emitting diodes (OLEDs) and charge-transport layers.
• Chemical Synthesis: Employed as a versatile scaffold for medicinal chemistry and drug discovery programs, enabling structure-activity relationship (SAR) studies.
• Fluorine Chemistry: The trifluoromethoxy group makes it a valuable compound for research in fluorine chemistry and the development of fluorinated analogs with enhanced properties.

Basic Information

Product Name	4-Hydroxy-7-Trifluoromethoxyquinoline
CAS No.	53985-75-4
Molecular Formula	C₁₀H₆F₃NO₂
Molecular Weight	229.16 g/mol
Synonyms	7-(Trifluoromethoxy)-4-quinolinol; 4-Quinolinol, 7-(trifluoromethoxy)-; 7-Trifluoromethoxy-4-hydroxyquinoline; 4-Hydroxy-7-trifluoromethoxyquinoline; 7-Trifluoromethoxyquinolin-4-ol; Quinolin-4-ol, 7-(trifluoromethoxy)-
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-7-Trifluoromethoxyquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.