Description

3-Methoxy-5-(Trifluoromethyl)Benzoic Acid is a high-value trifluoromethylated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, combining a methoxy group with a strongly electron-withdrawing trifluoromethyl group, makes it indispensable for modulating the physicochemical properties of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group improves lipophilicity and biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for advanced electronic materials, contributing to the molecular design of dyes, pigments, and charge-transport layers in display technologies.
• Organic Ligand & Catalyst Development: Employed to synthesize sophisticated ligands for metal-organic frameworks (MOFs) and asymmetric catalysis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic & Industrial R&D: Used in research laboratories for method development and exploring new chemical spaces in medicinal and synthetic chemistry.

Basic Information

Product Name	3-Methoxy-5-(Trifluoromethyl)Benzoic Acid
CAS No.	53985-48-1
Molecular Formula	C9H7F3O3
Molecular Weight	220.15 g/mol
Synonyms	5-(Trifluoromethyl)-3-methoxybenzoic Acid; 3-Methoxy-5-trifluoromethylbenzoic Acid; Benzoic acid, 3-methoxy-5-(trifluoromethyl)-; m-Methoxy-α,α,α-trifluoro-m-toluic Acid; 3-Methoxy-α,α,α-trifluoro-m-toluic Acid; 3-Methoxy-5-(trifluoromethyl)benzenecarboxylic Acid
EINECS	Contact for details

Quality Control

Our 3-Methoxy-5-(Trifluoromethyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. Due to its acidic nature, handle with appropriate engineering controls.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.