Description

3-(4-Hydroxy-3-Iodophenyl)Propionic Acid is a high-purity iodinated aromatic carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a phenolic hydroxyl and a propionic acid group ortho to an iodine atom, makes it a versatile intermediate for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of thyroid hormone analogs, non-steroidal anti-inflammatory drug (NSAID) candidates, and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of new herbicides and plant growth regulators that leverage its halogenated aromatic core.
• Liquid Crystal & OLED Materials: Serves as a building block for iodinated monomers used in advanced electronic displays and organic light-emitting diodes (OLEDs).
• Bioconjugation & Probe Development: The carboxylic acid group allows for coupling to proteins, peptides, or other biomolecules to create diagnostic probes or targeted conjugates.
• Academic & Contract Research: A valuable reagent for methodological studies in cross-coupling reactions (e.g., Suzuki, Heck) and other transition metal-catalyzed processes.
• Fine Chemical Production: Intermediate for the manufacture of specialty chemicals, dyes, and complex fragrance compounds.

Basic Information

Item	Details
Product Name	3-(4-Hydroxy-3-Iodophenyl)Propionic Acid
CAS No.	53937-19-2
Molecular Formula	C9H9IO3
Molecular Weight	292.07 g/mol
Synonyms	3-(4-Hydroxy-3-iodophenyl)propanoic acid; 4-Hydroxy-3-iodohydrocinnamic acid; 3-(3-Iodo-4-hydroxyphenyl)propionic acid; 53937-19-2; (4-Hydroxy-3-iodophenyl)propionic acid; 3-(4-Hydroxy-3-iodo-phenyl)-propionic acid; Hydrocinnamic acid, 4-hydroxy-3-iodo-
EINECS	Contact for details

Quality Control

Our 3-(4-Hydroxy-3-Iodophenyl)Propionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after the original container has been opened.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.