Description

(S)-1-Phenylethylhydroxylamine is a high-purity chiral amine building block of significant importance in asymmetric synthesis. Its primary value lies in its utility as a versatile chiral auxiliary and resolving agent for the preparation of enantiomerically pure compounds. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce stereochemical control into their synthetic pathways.

Application

• Chiral Auxiliary in Asymmetric Synthesis: Used to induce chirality in the synthesis of complex molecules, including active pharmaceutical ingredients (APIs).
• Resolution of Racemic Mixtures: Employed as a resolving agent to separate enantiomers of carboxylic acids and other chiral compounds.
• Pharmaceutical Intermediate: A key precursor in the synthesis of chiral drugs, particularly those targeting neurological and cardiovascular diseases.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and pesticides for enhanced efficacy.
• Ligand Preparation: Serves as a starting material for the synthesis of chiral ligands used in catalytic asymmetric reactions.
• Academic & Industrial R&D: A critical reagent for methodological development in organic chemistry and process chemistry optimization.

Basic Information

Product Name	(S)-1-Phenylethylhydroxylamine
CAS No.	53933-47-4
Molecular Formula	C8H11NO
Molecular Weight	137.18 g/mol
Synonyms	(S)-α-Methylbenzylhydroxylamine; (S)-(-)-1-Phenylethylhydroxylamine; (S)-N-Hydroxy-α-phenylethylamine; (1S)-1-Phenylethan-1-amine, N-hydroxy-; (S)-PEHA; L-(-)-1-Phenylethylhydroxylamine; (S)-N-Hydroxy-1-phenylethanamine
EINECS	Contact for details

Quality Control

Our (S)-1-Phenylethylhydroxylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and enantiomeric purity, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity (HPLC/GC), chiral purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.