Description

(+)-Anabasinehydrochloride CAS NO 53912-89-3 is the hydrochloride salt of the naturally occurring alkaloid (+)-Anabasine, a structural analog of nicotine. This high-purity chiral compound is a critical reference standard and intermediate in advanced pharmaceutical and biochemical research. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and life science sectors for developing novel therapeutics and studying nicotinic acetylcholine receptor (nAChR) interactions.

Application

• Pharmaceutical Research & Development: Serves as a key chiral building block and reference standard in the synthesis and study of novel nAChR-targeting drugs for neurological conditions.
• Biochemical & Pharmacological Studies: Used as a selective ligand and tool compound for investigating the function and modulation of nicotinic acetylcholine receptors in vitro and in vivo.
• Agrochemical Research: Employed as an intermediate in the development of next-generation, selective neonicotinoid-inspired insecticides and pest control agents.
• Analytical Chemistry: Functions as a certified reference material (CRM) for method development, validation, and quality control in HPLC, LC-MS, and GC-MS analyses.
• Academic Research: Essential for university and institutional labs conducting studies in neurochemistry, toxicology, and natural product chemistry.

Basic Information

Product Name	(+)-Anabasinehydrochloride
CAS No.	53912-89-3
Molecular Formula	C10H15ClN2
Molecular Weight	198.69 g/mol
Synonyms	(+)-Anabasine HCl; (S)-Anabasine Hydrochloride; (S)-3-(Piperidin-2-yl)pyridine hydrochloride; L-Anabasine Hydrochloride; 2-(3-Pyridyl)piperidine Hydrochloride; Neonicotine Hydrochloride; (S)-Anabasine Monohydrochloride
EINECS	Contact for details

Quality Control

Our (+)-Anabasinehydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for research and development applications. A detailed Certificate of Analysis (COA) providing HPLC purity, chiral excess, and identity confirmation is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.