Description

H-Gla-Oh CAS NO 53861-57-7 is a high-purity, non-proteinogenic amino acid derivative of significant interest in advanced chemical synthesis. This compound serves as a critical chiral building block and intermediate for the development of complex bioactive molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for applications in peptide mimetics, drug discovery, and the synthesis of specialized agrochemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel active pharmaceutical ingredients (APIs) and peptide-based therapeutics.
• Peptidomimetics Research: Used in medicinal chemistry to design and synthesize peptide analogs with enhanced metabolic stability and bioavailability.
• Bioconjugation: Acts as a linker or spacer molecule for attaching functional groups, labels, or drugs to proteins, antibodies, or other biomolecules.
• Agrochemical Synthesis: Employed as a building block for creating advanced, target-specific herbicides or plant growth regulators.
• Biochemical Research: Utilized as a substrate or inhibitor in enzymatic studies and metabolic pathway investigations.
• Fine Chemical Production: Serves as a precursor for manufacturing specialty chemicals, flavors, and fragrances requiring specific stereochemistry.

Basic Information

Product Name	H-Gla-Oh CAS NO 53861-57-7
CAS No.	53861-57-7
Molecular Formula	C5H9NO4
Molecular Weight	147.13 g/mol
Synonyms	L-2-Aminoglutaric acid 5-methyl ester; (2S)-2-Aminopentanedioic acid 5-methyl ester; H-Gla-OMe; Methyl L-2-aminoglutarate; Methyl (S)-2-aminopentanedioate; 5-O-Methyl-L-glutamic acid; L-Glutamic acid 5-methyl ester
EINECS	Contact for details

Quality Control

Our H-Gla-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for every batch, detailing key parameters such as assay, enantiomeric purity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.