Description

Retinol Phosphate is a phosphorylated derivative of Vitamin A (retinol), a key intermediate in the visual cycle and cellular signaling pathways. This compound is valued for its enhanced stability and bioavailability compared to retinol, making it a critical ingredient in advanced pharmaceutical and cosmeceutical formulations. It is primarily utilized by manufacturers in the nutraceutical, high-end skincare, and ophthalmic research sectors seeking innovative delivery systems for Vitamin A activity.

Application

• Pharmaceutical Intermediates: Serves as a key precursor in the synthesis of novel retinoid-based drugs and prodrugs targeting dermatological conditions and vision-related disorders.
• Advanced Cosmetic Actives: Incorporated into anti-aging serums, creams, and treatments for its role in cellular renewal and collagen synthesis, often in stabilized, encapsulated delivery systems.
• Nutraceutical Formulations: Used in the development of specialized dietary supplements where targeted release and improved metabolic handling of Vitamin A are required.
• Biochemical Research: Essential reagent in studies of retinoid metabolism, signal transduction, and the molecular biology of vision and cell differentiation.
• Cell Culture Media: Employed as a defined component in specialized media for culturing certain cell lines sensitive to retinoid signaling.

Basic Information

Product Name	Retinol Phosphate
CAS No.	53859-19-1
Molecular Formula	C20H31O6P
Molecular Weight	398.43 g/mol
Synonyms	Vitamin A Phosphate; Retinyl Phosphate; all-trans-Retinyl Phosphate; Retinol, dihydrogen phosphate; 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol dihydrogen phosphate; RO 1-5068
EINECS	Contact for details

Quality Control

Our Retinol Phosphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for high-purity applications. Certificates of Analysis (COA) documenting purity, related substances, and other critical parameters are provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) or as specified on the label. Due to its sensitivity to light and oxidation, prolonged exposure to air or light should be avoided. Keep the container in a dry, cool, and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.