Description

Tetroxoprim CAS NO 53808-87-0 is a synthetic antibacterial agent belonging to the diaminopyrimidine class, structurally related to trimethoprim. It is valued for its role as a potent inhibitor of bacterial dihydrofolate reductase (DHFR), which is critical for folate synthesis and microbial growth. This compound is primarily utilized in the pharmaceutical industry for research and development of antimicrobial formulations, as well as in veterinary medicine.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of advanced antibacterial agents and combination therapies.
• Veterinary Medicinal Products: Used in the development of treatments for bacterial infections in livestock and companion animals.
• Microbiological Research: Serves as a reference standard and active compound in studies targeting bacterial dihydrofolate reductase and mechanisms of antibiotic resistance.
• Combination Therapy Development: Investigated for use in synergistic combinations with sulfonamides or other antimicrobials to enhance efficacy and overcome resistance.
• API Synthesis: Employed in the manufacturing process of Active Pharmaceutical Ingredients (APIs) for specific antibacterial medications.

Basic Information

Product Name	Tetroxoprim
CAS No.	53808-87-0
Molecular Formula	C16H20N4O4
Molecular Weight	332.36 g/mol
Synonyms	2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine; Tetroxoprimum; ICI 156,088; NSC 351521; 5-[(3,4,5-Trimethoxyphenyl)methyl]-2,4-pyrimidinediamine
EINECS	Contact for details

Quality Control

Our Tetroxoprim is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via techniques such as HPLC, to ensure it meets high-grade standards suitable for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.