Description

n-[4-[[(4-Methyl-2-Pyrimidinyl)Amino]Sulphonyl]Phenyl]Acetamide CAS NO 127-73-1 is a specialized organic compound featuring a sulfonamide-linked pyrimidine-acetamide structure, serving as a critical building block in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and high-value fine chemicals, where precise molecular architecture is paramount. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel therapeutic agents and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of sulfonamide-based drug candidates, particularly for developing antimicrobial and diuretic agents.
• Agrochemical Research: Used in creating novel herbicides and fungicides, leveraging its bioactive pyrimidine-sulfonamide core.
• Fine Chemical Synthesis: Serves as a versatile building block for producing complex organic molecules in research and development laboratories.
• Biochemical Probe Development: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and target identification.
• Material Science: Potential intermediate for synthesizing specialty polymers or ligands with specific electronic or binding properties.

Basic Information

Item	Detail
Product Name	n-[4-[[(4-Methyl-2-Pyrimidinyl)Amino]Sulphonyl]Phenyl]Acetamide
CAS No.	127-73-1
Molecular Formula	C13H14N4O3S
Molecular Weight	306.34 g/mol
Synonyms	N-(4-((4-Methylpyrimidin-2-yl)sulfamoyl)phenyl)acetamide; 4-Acetamido-N-(4-methyl-2-pyrimidinyl)benzenesulfonamide; 4'-Acetamidosulfanilamide-4-methylpyrimidine; Sulfamethazine Impurity; Sulfadimidine Related Compound; N1-(4-Methyl-2-pyrimidinyl)sulfanilamide-4'-acetamide; 127-73-1
EINECS	204-866-7

Quality Control

Our n-[4-[[(4-Methyl-2-Pyrimidinyl)Amino]Sulphonyl]Phenyl]Acetamide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring the material meets the stringent requirements for pharmaceutical R&D and other high-purity applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.