Description

2-Bromo-1,4-dimethoxy-3-methylnaphthalene is a high-purity, synthetically valuable halogenated naphthalene derivative. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those with naphthalene-based scaffolds.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Building Block: The bromine and methoxy groups offer sites for further functionalization via cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitutions.
• Material Science: Potential monomer or precursor for constructing organic semiconductors, liquid crystals, or photochromic materials.
• Chemical Research: Serves as a standard or reagent in methodological studies and catalysis research within academic and industrial laboratories.

Basic Information

Product Name	2-Bromo-1,4-dimethoxy-3-methylnaphthalene
CAS No.	53772-33-1
Molecular Formula	C₁₃H₁₃BrO₂
Molecular Weight	281.15 g/mol
Synonyms	1,4-Dimethoxy-2-bromo-3-methylnaphthalene; 3-Methyl-2-bromo-1,4-dimethoxynaphthalene; 2-Bromo-3-methyl-1,4-naphthoquinone dimethyl ether; NSC 403116; 1,4-Naphthoquinone, 2-bromo-3-methyl-, dimethyl ether
EINECS	Contact for details

Quality Control

Our 2-Bromo-1,4-dimethoxy-3-methylnaphthalene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a Certificate of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for use as a pharmaceutical intermediate.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Purity (GC)	≥96.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.