Description

4(3H)-Quinazolinone, 2-Amino-6-(Hydroxymethyl)- is a versatile quinazolinone derivative, a key heterocyclic scaffold of significant interest in advanced organic synthesis. Its value lies in its bifunctional structure, featuring both an amino and a hydroxymethyl group, which makes it a crucial building block for constructing more complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Organic Synthesis Building Block: Utilized in medicinal chemistry for the construction of complex heterocyclic compounds and combinatorial libraries due to its reactive amino and hydroxymethyl functional groups.
• Agrochemical Research: Employed in the development of new herbicides and pesticides, where the quinazolinone core can impart specific biological activity.
• Material Science Research: Investigated as a monomer or precursor for the synthesis of specialty polymers and organic electronic materials.
• Biochemical Research: Used in the study of enzyme inhibition and as a scaffold for designing molecular probes and diagnostic agents.

Basic Information

Item	Detail
Product Name	4(3H)-Quinazolinone, 2-Amino-6-(Hydroxymethyl)-
CAS No.	53745-24-7
Molecular Formula	C9H9N3O2
Molecular Weight	191.19 g/mol
Synonyms	2-Amino-6-(hydroxymethyl)quinazolin-4(3H)-one; 2-Amino-6-(hydroxymethyl)-4(3H)-quinazolinone; 6-(Hydroxymethyl)-2-amino-4(3H)-quinazolinone; 2-Amino-6-hydroxymethylquinazolin-4-one; AQH; 2-Amino-6-(hydroxymethyl)-3H-quinazolin-4-one
EINECS	Contact for details

Quality Control

Every batch of 4(3H)-Quinazolinone, 2-Amino-6-(Hydroxymethyl)- undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality management system is designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), physical characteristics, and spectral data (IR, NMR) is provided with each shipment to guarantee traceability and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to store the material under an inert atmosphere or in a desiccator for long-term preservation to maintain stability and purity. Ideal storage temperature is between 2°C and 8°C.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.