Description

1,2:5,6-Di-o-Isopropylidene-D-Glucitol is a high-purity, protected sugar alcohol derivative, serving as a crucial chiral building block and intermediate in advanced organic synthesis. Its value lies in its ability to introduce stereochemical complexity and functional handles into target molecules with high fidelity. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs), specialty catalysts, and complex natural products.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of nucleoside analogs, antiviral drugs, and other biologically active molecules.
• Asymmetric Catalyst Ligand Precursor: Used in the preparation of chiral ligands for transition metal catalysis in enantioselective reactions.
• Fine Chemical Synthesis: Serves as a starting material or protected intermediate for complex carbohydrates, glycolipids, and other specialty chemicals.
• Agrochemical Research: Employed in the development of chiral pesticides and herbicides where specific stereochemistry is critical for activity.
• Academic & R&D: A valuable tool in synthetic organic chemistry research for methodology development and total synthesis projects.
• Polymer Science: Potential monomer or modifier for creating functionalized or biodegradable polymers.

Basic Information

Product Name	1,2:5,6-Di-o-Isopropylidene-D-Glucitol
CAS No.	53735-98-1
Molecular Formula	C12H20O6
Molecular Weight	260.28 g/mol
Synonyms	1,2:5,6-Di-O-isopropylidene-D-glucitol; Diacetone-D-glucitol; Diacetone-D-sorbitol; 1,2:5,6-Di-O-(1-methylethylidene)-D-glucitol; D-Glucitol, 1,2:5,6-bis-O-(1-methylethylidene)-; Diacetone sorbitol; (3R,4S,5R,6R)-2,2,7,7-Tetramethyl-3,4,5,6-bis(methylenedioxy)heptane
EINECS	258-714-5

Quality Control

Our 1,2:5,6-Di-o-Isopropylidene-D-Glucitol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, optical rotation measurement, and identity confirmation (IR, NMR) to ensure it meets the stringent requirements of research and production applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent absorption of atmospheric moisture, which may affect product quality and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Optical Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.