Description

Alka-Seltzer CAS NO 53663-74-4 is a widely recognized effervescent antacid and pain reliever formulation, primarily composed of aspirin, citric acid, and sodium bicarbonate. This compound is critical for providing rapid relief from heartburn, acid indigestion, and minor aches, leveraging a unique effervescent delivery system for faster absorption. It is an essential product for pharmaceutical manufacturers, contract development and production organizations (CDMOs), and distributors serving the global over-the-counter (OTC) healthcare market.

Application

• Pharmaceutical Formulations: Primary use in the manufacture of effervescent tablets for analgesic and antacid relief.
• Over-the-Counter (OTC) Medications: Key ingredient in branded and generic products for heartburn, sour stomach, and headache relief.
• Consumer Healthcare Products: Used in the production of fast-acting, water-soluble tablets and powders for direct consumer use.
• Clinical & Hospital Supplies: Sourced for use in hospital formularies and clinical settings for patient symptomatic relief.
• Contract Manufacturing: Supplied to CDMOs for the production of private-label and store-brand OTC remedies.
• Export & Global Distribution: Supplied in bulk to distributors serving international pharmaceutical and retail markets.

Basic Information

Product Name	Alka-Seltzer
CAS No.	53663-74-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Alka-Seltzer Original; Alka-Seltzer Effervescent; Aspirin-Citric Acid-Sodium Bicarbonate; Acetylsalicylic Acid-Citric Acid-Sodium Bicarbonate; OTC Antacid-Analgesic; Effervescent Antacid; Bayer Alka-Seltzer; Sodium Bicarbonate Compound
EINECS	Contact for details

Quality Control

Our Alka-Seltzer is manufactured under strict quality systems to ensure consistency and efficacy for pharmaceutical applications. Quality assurance includes rigorous testing for active ingredient assay, dissolution rate, effervescence time, and microbiological purity in line with cGMP guidelines. A comprehensive Certificate of Analysis (COA) is provided with each batch, documenting compliance with relevant pharmacopeial standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the product must be kept in original, moisture-proof packaging until use to prevent degradation and maintain effervescent properties.

Specification

Item	Specification
Appearance	White to off-white effervescent tablet
Identification (IR)	Complies
Assay (Aspirin)	325 mg per tablet ± 5%
Assay (Sodium Bicarbonate)	1916 mg per tablet ± 5%
Assay (Citric Acid)	1000 mg per tablet ± 5%
Dissolution	NLT 80% in 30 minutes
Effervescence Time	Complete within 2 minutes in water
Microbial Limits	Complies with USP <61> and <62>

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.