Description

(1R,2R)-1-Norpseudoephedrine HCl is a high-purity chiral amine hydrochloride salt, serving as a critical pharmaceutical intermediate and research chemical. Its defined stereochemistry is essential for applications requiring precise enantiomeric control, ensuring consistent performance in advanced synthesis. This compound is primarily sought by the pharmaceutical, biotechnology, and fine chemical industries for the development and production of active pharmaceutical ingredients (APIs), chiral catalysts, and reference standards.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of chiral drugs, particularly those targeting the central nervous system.
• Chiral Catalyst/Resolving Agent: Used in asymmetric synthesis to induce enantioselectivity in chemical reactions.
• Reference Standard: Serves as a certified standard for analytical method development and quality control in pharmaceutical laboratories.
• Biochemical Research: Utilized in pharmacological studies as a ligand or probe for adrenergic receptor research.
• Fine Chemical Synthesis: Intermediate for the preparation of complex organic molecules in academic and industrial R&D settings.

Basic Information

Product Name	(1R,2R)-1-Norpseudoephedrine HCl
CAS No.	53643-20-2
Molecular Formula	C9H14ClNO
Molecular Weight	187.66 g/mol
Synonyms	(1R,2R)-(-)-Norpseudoephedrine Hydrochloride; (1R,2R)-1-Phenyl-2-amino-1-propanol Hydrochloride; d-Norpseudoephedrine HCl; (1R,2R)-2-Amino-1-phenyl-1-propanol Hydrochloride; (R,R)-(-)-Norpseudoephedrine HCl; Cathine Hydrochloride (stereospecific); α-[(1R,2R)-2-Amino-1-hydroxypropyl]benzyl Alcohol Hydrochloride
EINECS	Contact for details

Quality Control

Our (1R,2R)-1-Norpseudoephedrine HCl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets high-grade specifications suitable for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.